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Some natural fat burner produced by the body. These include glucagon and growth hormone somatotropin. Fatburner also occur in food, to include alleged magnesium, linoleic acid and vitamin C, enzymes and L-carnitine, as well as caffeine.

Artificial Fatburner are made of natural and synthetic substances produced compounds that are added to the form of tablets, powder or liquid to the food. They are used to assist in reducing the body weight and in the context of bodybuilding. Sometimes they do contain substances which may be supplied in Germany legally limited (causing, for example, ephedrine), or adverse effects. The immediate intended effect of fat burners is doubted by many doctors and nutritionists.

Hydroxycut is sold at conventional retailers, online retailers, and through direct television marketing. Sold in the United States without ephedra, it was advertised as a weight-loss supplement to increase metabolism and reduce hunger cravings. Prior to May 2009, its primary ingredients included Garcinia cambogia, Gymnema sylvestre, chromium polynicotinate, caffeine, and green tea. Like many nutraceuticals, its efficacy is questionable and not well-supported by research. Some studies suggest that further research is warranted, though the mechanism through which Hydroxycut may operate remains unclear.

Hydroxycut was promoted as being created and endorsed by doctors. Television advertisements for Hydroxycut featured Jon Marshall, a graduate of Midwestern University's osteopathic medical school, and still in residency. Hydroxycut was also endorsed by its formulator, Marvin Heuer, Associate Clinical Professor in the Department of Family Medicine and Community Health at the University of Florida, and Former Chief Scientific Officer of Iovate Health Sciences, the company that markets the product.

In recent years, Hydroxycut had become available in several forms and formulas that did not contain ephedra.

They included:

Hydroxycut

Caffeine-Free Hydroxycut – similar to regular Hydroxycut but designed for caffeine-sensitive people.

Hydroxycut 24 - an around-the-clock type of weight-loss product that includes regular Hydroxycut for the daytime and the caffeine-free for the evening.

Hydroxycut Hardcore – a weight-loss supplement for bodybuilders or other sportspersons.

Hydroxycut Max! – a weight-loss supplement for female fitness competitors or other sportswomen.

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